![]() “This is an important next step after the PATS study that now shows that A2As can provide nearly equivalent ADHD symptom relief with fewer frequent adverse effects,” says Dr. But, more than 40 percent of children had irritability while taking it more than 20 percent experienced crying or were tearful, sad, or depressed. An encouraging follow-up studyĪn earlier landmark study conducted elsewhere, called the Preschool ADHD Treatment Study (PATS), found that treatment with the stimulant methylphenidate significantly reduced ADHD symptoms in children between the ages of 3 to 5.5 years. “The fact is that children taking the A2As had fewer difficulties with these side effects,” says Harstad.
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